Cyclophilin B deficiency enhances myocardial energy synthesis and protects against heart failure in preclinical models
CypB deficiency ameliorates CH and HF by enhancing cardiac energy production, providing a potential therapeutic target for CH and HF.
Authors
- Roubai Pan
- Qin Fan (ORCID: https://orcid.org/0000-0001-6099-5968)
- Rong Tao (ORCID: https://orcid.org/0000-0001-5766-1625)
- Qian Yang (ORCID: https://orcid.org/0000-0001-8778-4132)
- Lingfang Zhuang (ORCID: https://orcid.org/0000-0003-2723-3202)
- Xierenayi Tudi
- Xiao Zong
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-12-07
- DOI
- https://doi.org/10.1186/s12916-025-04563-4
- Primary Topic
- Signaling Pathways in Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00