Multiple arterial aneurysms involving the thoracoabdominal aorta and renal arteries in a young patient with possible heritable etiology: Two-stage open surgical repair management

Multilevel arterial aneurysm refers to aneurysms in multiple sites, such as the aorta, cerebral, or peripheral arteries, often caused by atherosclerosis, heritable thoracic aortic disease, inflammation, or infection. We report the case of a 48-year-old patient with multilevel arterial aneurysm managed with staged open surgical repair. The first surgery addressed an 11-cm abdominal aortic aneurysm and renal artery aneurysms, followed by thoracoabdominal aortic aneurysm repair. Both procedures were uneventful, with successful grafting and preserved organ perfusion. Six-month follow-up computed tomography scan showed no complications. Postoperative genetic testing revealed two variants of uncertain significance (PKD1, FBN1). Open surgical repair proved safe and effective in a high-volume center.