Based on the PINK1/Parkin signaling pathway, the protective effect of salidroside on cerebral ischemia-reperfusion injury in male rats was investigated
Salidroside may inhibit iron death by activating the PINK 1 / Parkin signaling pathway and thereby reduce cerebral ischemia-reperfusion injury. Targeted regulation of this pathway may become an important strategy to interfere with CIRI.
Authors
- Jun Jie Tan (ORCID: https://orcid.org/0000-0002-7027-6657)
- Yanwei Li (ORCID: https://orcid.org/0000-0003-3828-9754)
- Ting Dong (ORCID: https://orcid.org/0009-0000-7050-9820)
- H. Wang (ORCID: https://orcid.org/0009-0001-2467-5331)
Institutions
- Henan Psychiatric Hospital (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108519
- Primary Topic
- Medicinal Plants and Bioactive Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00