Protective effects of biomimetic Cu-Zn-MOF against DOX-Induced cardiotoxicity through inhibiting oxidative stress and ferroptosis
In all, our study demonstrates that CZM possesses excellent enzyme-mimicking activities, along with good biosafety and biocompatibility. These findings highlight CZM's potential as a novel cardioprotective drug for mitigating DIC.
Authors
- Changnan Wang
- Xiaoyan Zhang (ORCID: https://orcid.org/0000-0002-3193-1401)
- Song Zhang (ORCID: https://orcid.org/0000-0002-1929-8316)
- Jian Wang (ORCID: https://orcid.org/0000-0001-5184-7023)
- Meng Zhao
- Hongming Zhu (ORCID: https://orcid.org/0009-0007-4928-527X)
Institutions
- Shanghai University (CN)
- Shanghai Medical College of Fudan University (CN)
- East China University of Science and Technology (CN)
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
- XinHua Hospital (CN)
- Shanghai East Hospital (CN)
- East China Normal University (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1186/s12951-025-03902-0
- Primary Topic
- Metal-Organic Frameworks: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00