C-reactive protein levels and behavioural outcomes in mid-childhood in very preterm and term born children
We show no evidence that prematurity or perinatal inflammation are associated with salivary CRP in mid-childhood, nor that perinatal inflammatory insults are related to later behavioural outcomes in our cohort of preterm children. Our findings support an association between salivary CRP and behavioural outcomes in mid-childhood. Further research is needed to understand the interplay between inflammation and behavioural and emotional regulation throughout childhood.
Authors
- A. David Edwards (ORCID: https://orcid.org/0000-0003-4801-7066)
- Paola Dazzan (ORCID: https://orcid.org/0000-0002-8427-3617)
- Serena J. Counsell (ORCID: https://orcid.org/0000-0002-8033-5673)
- Andrew J. Lawrence (ORCID: https://orcid.org/0000-0002-1420-3381)
- Emily Simonoff (ORCID: https://orcid.org/0000-0002-5450-0823)
- Naghmeh Nikkheslat (ORCID: https://orcid.org/0000-0002-9427-6715)
- Chiara Nosarti (ORCID: https://orcid.org/0000-0001-6305-9710)
- Laila Hadaya (ORCID: https://orcid.org/0000-0002-6484-1090)
- Ira Kleine (ORCID: https://orcid.org/0000-0002-6500-9407)
- Zeyuan Sun (ORCID: https://orcid.org/0000-0002-2309-8149)
- Carmine M. Pariante (ORCID: https://orcid.org/0000-0002-9132-5091)
- Alexandria O’Reilly Mescall
Institutions
- King's College London (GB)
- South London and Maudsley NHS Foundation Trust (GB)
Publication Details
- Journal
- Brain Behavior and Immunity
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1016/j.bbi.2025.106213
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 0.00