Small cell lung cancer invading the pulmonary artery misdiagnosed as pulmonary thromboembolism: a case report

We report a case of small cell lung cancer (SCLC) invading the pulmonary artery, initially misdiagnosed as pulmonary thromboembolism (PTE). The patient received anticoagulation therapy for 3 months without improvement. Subsequent positron emission tomography-computed tomography (PET-CT) revealed hypermetabolic lesions suspicious for malignancy, and bronchoscopy with biopsy confirmed SCLC. This case highlights the diagnostic challenge of distinguishing pulmonary artery invasion by tumor from PTE, and underscores the critical role of PET-CT and timely histopathological confirmation in guiding clinical management.

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Publication Details

Journal
Journal of Cardiothoracic Surgery
Published
2025-12-06
DOI
https://doi.org/10.1186/s13019-025-03725-y
Primary Topic
Cardiac tumors and thrombi
Type
article
Field-Weighted Citation Impact
0.00
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article

Small cell lung cancer invading the pulmonary artery misdiagnosed as pulmonary thromboembolism: a case report

Xinjuan Yu, Wanming Hao, Yanmiao Li, Yanling Zhang et al.
Journal of Cardiothoracic Surgery
Cardiac tumors and thrombi
article

Small cell lung cancer invading the pulmonary artery misdiagnosed as pulmonary thromboembolism: a case report

Xinjuan Yu, Wanming Hao, Yanmiao Li, Yanling Zhang, Shanshan Yuan, Shufang Sun, Ziwei Kou
article en

Abstract

We report a case of small cell lung cancer (SCLC) invading the pulmonary artery, initially misdiagnosed as pulmonary thromboembolism (PTE). The patient received anticoagulation therapy for 3 months without improvement. Subsequent positron emission tomography-computed tomography (PET-CT) revealed hypermetabolic lesions suspicious for malignancy, and bronchoscopy with biopsy confirmed SCLC. This case highlights the diagnostic challenge of distinguishing pulmonary artery invasion by tumor from PTE, and underscores the critical role of PET-CT and timely histopathological confirmation in guiding clinical management.

Journal of Cardiothoracic SurgeryVol. 21(1)
Qingdao University (CN), Weifang Medical University (CN), Qingdao Municipal Hospital (CN), Yancheng Central Blood Station (CN)
Openalex Percentile: Top 44%
Cardiac tumors and thrombi
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Small cell lung cancer invading the pulmonary artery misdiagnosed as pulmonary thromboembolism: a case report — Xinjuan Yu, Wanming Hao, et al. · Journal of Cardiothoracic Surgery (2025) | TGRS Research Map | TGRS