Diagnostic Performance of Fecal Biomarkers and Their Correlation with Endoscopic Severity in Immune Checkpoint Inhibitor-Related Colitis

Fecal biomarkers were correlated with endoscopic activity and effectively identified patients with endoscopically active IMDC. Our findings suggest that these biomarkers may be valuable tools for the diagnosis and assessment of treatment response in IMDC.

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Publication Details

Journal
Digestion
Published
2025-12-06
DOI
https://doi.org/10.1159/000549888
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
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article

Diagnostic Performance of Fecal Biomarkers and Their Correlation with Endoscopic Severity in Immune Checkpoint Inhibitor-Related Colitis

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Digestion
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Diagnostic Performance of Fecal Biomarkers and Their Correlation with Endoscopic Severity in Immune Checkpoint Inhibitor-Related Colitis

K Takenaka, Shuji Hibiya, Ami Kawamoto, Yasuo Hamamoto, Yoshihito Kano, Toshimitsu Fujii, Ryo Morikawa, Hiromichi Shimizu, Kazuo Ohtsuka, Mitsukuni Suenaga, Ryuichi Okamoto, Akiko Tamura
article en

Abstract

Fecal biomarkers were correlated with endoscopic activity and effectively identified patients with endoscopically active IMDC. Our findings suggest that these biomarkers may be valuable tools for the diagnosis and assessment of treatment response in IMDC.

Digestion
Tokyo Metropolitan Institute of Medical Science (JP), Temple University, Japan (JP)
Openalex Percentile: Top 46%
Cancer Immunotherapy and Biomarkers
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