Eimeria tenella apical membrane 2 overexpression enhances pathogenicity and immunity in chickens
The present data indicated that EtAMA2 had dual functions as a virulence factor critical for early invasion and a promising vaccine antigen. This study thereby provided new insights for future drug target screening and development of a vaccine against coccidiosis.
Authors
- Shanbo Wu
- Jiayu Bai
- Jinwen Wang (ORCID: https://orcid.org/0000-0003-3499-3955)
- Yu Yu (ORCID: https://orcid.org/0000-0002-0209-0586)
- Lihui Wang (ORCID: https://orcid.org/0000-0002-6538-0855)
- Shunhai Zhu
- Hui Dong (ORCID: https://orcid.org/0000-0003-1905-5936)
- Qiping Zhao
- Wenqi Han (ORCID: https://orcid.org/0000-0002-0093-4474)
- Han HongYu
- Fanghe Zhao
Institutions
- Shanghai Veterinary Research Institute (CN)
- Chinese Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1186/s13071-025-07185-0
- Primary Topic
- Coccidia and coccidiosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00