Adjuvant ovarian function suppression and aromatase inhibitors in premenopausal patients with hormone receptor and HER2 positive breast cancer, by timing of chemotherapy and trastuzumab and response to neoadjuvant therapy
OFS + AI were associated with better DDFS in patients with RD after neoadjuvant therapy. Our findings can assist shared decision-making on adjuvant endocrine therapy of these patients.
Authors
- Shani Paluch–Shimon (ORCID: https://orcid.org/0000-0002-6677-2199)
- Bilgeşah Kılıçtaş (ORCID: https://orcid.org/0000-0002-2485-7901)
- Giuseppe Fotia (ORCID: https://orcid.org/0000-0002-2071-8971)
- Areen Abu Remilah
- Katarzyna Pogoda (ORCID: https://orcid.org/0000-0002-9902-711X)
- Tal Sella (ORCID: https://orcid.org/0000-0003-2030-9200)
- Anastasia Constantinidou (ORCID: https://orcid.org/0000-0001-5316-7574)
- Lucía González Cortijo (ORCID: https://orcid.org/0000-0003-2082-670X)
- Nathalie E. Ruyssers
- Elena Vicente-Rubio
- Eleonora De Maio D’Esposito
- Leonor Vasconcelos de Matos (ORCID: https://orcid.org/0000-0001-9568-238X)
- Sofie Demasure
- Ezequiel Lozano Chiappe (ORCID: https://orcid.org/0000-0003-0890-6854)
- Helena Gouveia (ORCID: https://orcid.org/0000-0003-0841-194X)
- Muhammed Mustafa ATCI
- Hans Wildiers (ORCID: https://orcid.org/0000-0001-8990-7837)
- Vivianne C. G. Tjan‐Heijnen (ORCID: https://orcid.org/0000-0002-3935-7440)
- Ana Fortuna (ORCID: https://orcid.org/0000-0001-5368-2410)
- İrfan Çiçin (ORCID: https://orcid.org/0000-0002-7584-3868)
- Barbro Linderholm (ORCID: https://orcid.org/0000-0003-1531-630X)
- Jalal Baranseh (ORCID: https://orcid.org/0000-0002-5748-1330)
- Mehmet Artaç (ORCID: https://orcid.org/0000-0003-2335-3354)
- Greet Huygh
- Nawale Hajjaji (ORCID: https://orcid.org/0000-0002-8500-2309)
- Frederieke van Duijnhoven (ORCID: https://orcid.org/0000-0003-3694-4049)
- Ottavia Amato (ORCID: https://orcid.org/0000-0002-3690-8542)
- Erika Matos (ORCID: https://orcid.org/0000-0001-5144-1285)
- Ayelet Shai (ORCID: https://orcid.org/0000-0001-9502-8441)
- Eurydice Angeli
- Laurent Rosset
- Matteo Lambertini
- Natali Shirron (ORCID: https://orcid.org/0009-0003-5509-3937)
- Patrick Neven
- Claudio Venieri
Institutions
- Champalimaud Foundation (PT)
- Universidad de Las Palmas de Gran Canaria (ES)
- Hebrew University of Jerusalem (IL)
- Sheba Medical Center (IL)
- Hadassah Medical Center (IL)
- Maastricht University Medical Centre (NL)
- AZ Groeninge (BE)
- Sahlgrenska University Hospital (SE)
- Rambam Health Care Campus (IL)
- Shaare Zedek Medical Center (IL)
- Institute of Oncology Ljubljana (SI)
- Jerusalem Multidisciplinary College (IL)
- Institut universitaire du cancer de Toulouse Oncopole (FR)
- Fribourg Development Agency (CH)
- Necmettin Erbakan University (TR)
- Hospital Universitario Quirónsalud Madrid (ES)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- Istinye University (TR)
- Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NL)
- Hôpital Avicenne (FR)
- Centre Oscar Lambret (FR)
- AZ Turnhout (BE)
- Bank of Cyprus Oncology Center (CY)
- Ospedale Policlinico San Martino (IT)
- The Maria Sklodowska-Curie National Research Institute of Oncology (PL)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- ASST Fatebenefratelli Sacco (IT)
- AZ Sint-Lucas (BE)
- KU Leuven (BE)
Publication Details
- Journal
- The Breast
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1016/j.breast.2025.104669
- Citations
- 1
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 1.82