Predicting venous thromboembolism risk from endogenous thrombin potential-based normalized activated protein C sensitivity ratio assay: toward early assessment of combined oral contraceptives
Our model, based on mean nAPCsr, provides a reliable, biomarker-based approach for predicting population-based COC-related VTE risk. This strategy could help shorten the time between product launch and population-based risk assessment.
Authors
- Laure Morimont (ORCID: https://orcid.org/0000-0001-9195-304X)
- Jonathan Douxfils (ORCID: https://orcid.org/0000-0002-7644-5298)
- Jean‐Michel Foidart (ORCID: https://orcid.org/0000-0002-6182-6303)
- Mitchell D. Creinin
- Ulysse Gaspard
Institutions
- University of Namur (BE)
- University of Liège (BE)
- Centre Hospitalier Universitaire de Clermont-Ferrand (FR)
- University of California, Davis (US)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1016/j.rpth.2025.103285
- Citations
- 1
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.77