Pathological fractures as an adverse prognostic factor in chondrosarcoma: Results of a systematic review, meta-analysis and institutional case series
Pathological fractures entail a significantly adverse prognosis in chondrosarcoma, particularly in high-grade and dedifferentiated subtypes and within the first 5 years of follow-up. Our institutional data corroborates <i>meta</i>-analysis findings. These results underscore the importance of personalized surgical management and intensive outcome monitoring for CS patients presenting with PF.
Authors
- Felix Klingler
- Georg W. Herget (ORCID: https://orcid.org/0000-0002-6225-0852)
- Hagen Schmal (ORCID: https://orcid.org/0000-0002-8801-2385)
- Nikos Karvouniaris (ORCID: https://orcid.org/0009-0009-0015-5209)
- Julian P. Maier (ORCID: https://orcid.org/0000-0002-2957-9031)
- Kilian Reising
- Ida Peiss
Institutions
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
- Odense University Hospital (DK)
Publication Details
- Journal
- Journal of bone oncology
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1016/j.jbo.2025.100735
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Albert-Ludwigs-Universität Freiburg
- Medizinische Fakultät der Albert-Ludwigs-Universität Freiburg