Potential Therapeutic Role of GLP-1 Receptor Agonists in the Management of Opioid Use Disorders: A Literature Review
Although early findings are encouraging, further research is needed to confirm these results, optimize dosing regimens, and clarify the underlying mechanisms of action. Given the interplay between metabolic and neuropsychiatric factors in OUD, GLP-1 receptor agonists offer a unique therapeutic advantage. Large-scale clinical trials are essential to determine their long-term efficacy, safety, and integration into comprehensive OUD treatment plans.
Authors
- Medha Gopal (ORCID: https://orcid.org/0009-0002-3063-3856)
- Jonathan Quinonez (ORCID: https://orcid.org/0000-0002-1900-0583)
- S Noorani (ORCID: https://orcid.org/0009-0008-9960-9962)
- D.M. Boothe (ORCID: https://orcid.org/0009-0008-2435-597X)
- Kyla D. Groves (ORCID: https://orcid.org/0009-0009-9454-6998)
- Skylar Bronson (ORCID: https://orcid.org/0009-0009-0322-0029)
Institutions
- St. George's University (GD)
- California Miramar University (US)
- Riverview Medical Center (US)
- St. Matthew's University (KY)
- Community Health Systems - Merit Health River Oaks (US)
- American University of the Caribbean School of Medicine (SX)
Publication Details
- Journal
- Addiction and Health
- Published
- 2025-11-22
- DOI
- https://doi.org/10.34172/ahj.1682
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00