Characterizing patterns of opioid and stimulant use by route and associations with non-fatal overdose and xylazine use in people who have injected drugs from Baltimore, MD, 2023–2024

We provide one of the most comprehensive summaries of substance use during the fourth wave in Baltimore, a city with the highest rate of fatal overdose in the US during the study period. Use of multiple substances was common, and many participants reported injection. Overdose prevention should be targeted to those injecting both drugs as this pattern had heightened overdose risk.

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Publication Details

Journal
Drug and Alcohol Dependence Reports
Published
2025-12-06
DOI
https://doi.org/10.1016/j.dadr.2025.100403
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Characterizing patterns of opioid and stimulant use by route and associations with non-fatal overdose and xylazine use in people who have injected drugs from Baltimore, MD, 2023–2024

Kenneth A. Feder, Liz M. Martínez-Ocasio, Shruti H. Mehta, Becky L. Genberg et al.
Drug and Alcohol Dependence Reports
Opioid Use Disorder Treatment
article

Characterizing patterns of opioid and stimulant use by route and associations with non-fatal overdose and xylazine use in people who have injected drugs from Baltimore, MD, 2023–2024

Kenneth A. Feder, Liz M. Martínez-Ocasio, Shruti H. Mehta, Becky L. Genberg, Danielle German, Catherine Tomko, Javier Cepeda, Jacqueline E. Rudolph, Gregory Dale Kirk
article en

Abstract

We provide one of the most comprehensive summaries of substance use during the fourth wave in Baltimore, a city with the highest rate of fatal overdose in the US during the study period. Use of multiple substances was common, and many participants reported injection. Overdose prevention should be targeted to those injecting both drugs as this pattern had heightened overdose risk.

Drug and Alcohol Dependence ReportsVol. 18
Johns Hopkins University (US), Johns Hopkins Medicine (US)
Openalex Percentile: Top 50%
Opioid Use Disorder Treatment
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Characterizing patterns of opioid and stimulant use by route and associations with non-fatal overdose and xylazine use in people who have injected drugs from Baltimore, MD, 2023–2024 — Kenneth A. Feder, Liz M. Martínez-Ocasio, et al. · Drug and Alcohol Dependence Reports (2025) | TGRS Research Map | TGRS