Outcomes and antimicrobial usage in preterm neonates < 34 weeks gestation with culture-negative neonatal sepsis: a prospective observational study

In preterm neonates, composite outcome of mortality and major morbidities did not differ significantly between those with CNNS and CPNS. However, a considerable proportion of CNNS neonates received a prolonged course of higher antibiotics. Thus, there is a need for strategies to improve clinical outcomes and strengthen adherence to antibiotic stewardship principles.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-12-06
DOI
https://doi.org/10.1186/s12879-025-12288-1
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
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article

Outcomes and antimicrobial usage in preterm neonates < 34 weeks gestation with culture-negative neonatal sepsis: a prospective observational study

Vijay Kumar, Rachita Sarangi, Jiaming Rao, Deepak Nanda et al.
BMC Infectious Diseases
Neonatal and Maternal Infections
article

Outcomes and antimicrobial usage in preterm neonates < 34 weeks gestation with culture-negative neonatal sepsis: a prospective observational study

Vijay Kumar, Rachita Sarangi, Jiaming Rao, Deepak Nanda, Ratan Das, Pragnya Paramita Jena
article en

Abstract

In preterm neonates, composite outcome of mortality and major morbidities did not differ significantly between those with CNNS and CPNS. However, a considerable proportion of CNNS neonates received a prolonged course of higher antibiotics. Thus, there is a need for strategies to improve clinical outcomes and strengthen adherence to antibiotic stewardship principles.

BMC Infectious DiseasesVol. 26(1)
Institute of Medical Sciences and Sum Hospital (IN)
Openalex Percentile: Top 50%
Neonatal and Maternal Infections
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