Evaluating the Diagnostic Utility of Cystatin C versus Creatinine in Chronic Kidney Disease: A Cross-Sectional Analysis
Serum cystatin C is a sensitive and reliable biomarker for CKD detection, demonstrating superior correlation with eGFR<sub>Cr-Cys</sub> compared to creatinine. Its diagnostic performance is especially valuable in early-stage disease and high-risk populations. Integrating cystatin C into routine clinical practice could enhance early diagnosis and improve patient outcomes, though cost and assay availability remain barriers.
Authors
- Ravi Shekhar (ORCID: https://orcid.org/0009-0005-4123-4190)
- Prit Pal Singh (ORCID: https://orcid.org/0000-0003-4600-1693)
- Praveen Kumar
- Bandana Kumari (ORCID: https://orcid.org/0000-0001-5395-413X)
- P. V. Sagar (ORCID: https://orcid.org/0009-0002-1452-8909)
Institutions
- Indira Gandhi Institute of Medical Sciences (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Cureus
- Published
- 2025-12-06
- DOI
- https://doi.org/10.7759/cureus.98573
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00