MedFact-R1: Towards Factual Medical Reasoning Via Pseudo-Label Augmentation
Ensuring factual consistency and reliable reasoning remains a critical challenge for medical vision-language models. We introduce MedFact-R1, a two-stage framework that integrates external knowledge grounding with reinforcement learning to improve the factual medical reasoning. The first stage uses pseudo-label supervised fine-tuning (SFT) to incorporate external factual expertise; while the second stage applies Group Relative Policy Optimization (GRPO) with four tailored factual reward signals to encourage self-consistent reasoning at deployment time without relying on external RAG. Across three public medical QA benchmarks, MedFact-R1 delivers up to 22.5% absolute improvement in factual accuracy over previous state-of-the-art methods. Ablation studies highlight the necessity of pseudo-label SFT cold start and validate the contribution of each GRPO reward, underscoring the synergy between knowledge grounding and RL-driven reasoning for trustworthy medical AI. Codes are released at https://github.com/Garfieldgengliang/MEDFACT-R1.
Authors
- Gengliang Li
- Bin Li (ORCID: https://orcid.org/0000-0001-6918-0749)
- Linlin Yang
- R. S. Chen (ORCID: https://orcid.org/0009-0008-0197-1147)
- Guodong Ding
Institutions
- HealthInsight (US)
Publication Details
- Published
- 2026-04-21
- DOI
- https://doi.org/10.1109/icassp55912.2026.11462237
- Primary Topic
- Multimodal Machine Learning Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China