Non-intrusive parametrized-background data-weak reconstruction of cardiac displacement fields from sparse MRI-like observations

Abstract Personalized cardiac diagnostics requires accurate reconstruction of myocardial displacement fields from sparse clinical imaging data. In this work, we apply the Parametrized-Background Data-Weak (PBDW) approach to three-dimensional (3D) cardiac displacement field reconstruction from limited magnetic resonance image-like observations. We introduce two methodological enhancements: (i) an H -size minibatch worst-case orthogonal matching pursuit algorithm that improves Sensor Selection (SSEL) while maintaining reconstruction accuracy, and (ii) memory optimisation techniques exploiting block matrix structures in vectorial problems. We demonstrate the effectiveness of the method through validation on a three-dimensional left ventricular model with simulated scar tissue. Starting with noise-free reconstruction, we systematically incorporate Gaussian noise and spatial sparsity mimicking realistic Magnetic Resonance Image acquisition protocols. Results show exceptional accuracy in noise-free conditions with relative $$L_2$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>L</mml:mi> <mml:mn>2</mml:mn> </mml:msub> </mml:math> error of $${1e-5}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mn>1</mml:mn> <mml:mi>e</mml:mi> <mml:mo>-</mml:mo> <mml:mn>5</mml:mn> </mml:mrow> </mml:math> , robust performance with 10% noise achieving relative $$L_2$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>L</mml:mi> <mml:mn>2</mml:mn> </mml:msub> </mml:math> error of $${1e-2}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mn>1</mml:mn> <mml:mi>e</mml:mi> <mml:mo>-</mml:mo> <mml:mn>2</mml:mn> </mml:mrow> </mml:math> , and effective reconstruction from sparse measurements with relative $$L_2$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>L</mml:mi> <mml:mn>2</mml:mn> </mml:msub> </mml:math> error of $${1e-2}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mn>1</mml:mn> <mml:mi>e</mml:mi> <mml:mo>-</mml:mo> <mml:mn>2</mml:mn> </mml:mrow> </mml:math> . The online reconstruction achieves sub-second computation times for a given patient geometry, enabling rapid clinical feedback and parameter studies that would be prohibitive with full Finite Element simulations, demonstrating significant potential for integration into clinical cardiac modelling workflows.

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Publication Details

Journal
Computational Mechanics
Published
2026-04-27
DOI
https://doi.org/10.1007/s00466-026-02763-0
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00

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article

Non-intrusive parametrized-background data-weak reconstruction of cardiac displacement fields from sparse MRI-like observations

Federica Caforio, Christoph M. Augustin, Matthias A. F. Gsell, Gundolf Haase et al.
Computational Mechanics
Cardiac Imaging and Diagnostics
article

Non-intrusive parametrized-background data-weak reconstruction of cardiac displacement fields from sparse MRI-like observations

Federica Caforio, Christoph M. Augustin, Matthias A. F. Gsell, Gundolf Haase, Elias Karabelas, Francesco C. Mantegazza
article en

Abstract

Abstract Personalized cardiac diagnostics requires accurate reconstruction of myocardial displacement fields from sparse clinical imaging data. In this work, we apply the Parametrized-Background Data-Weak (PBDW) approach to three-dimensional (3D) cardiac displacement field reconstruction from limited magnetic resonance image-like observations. We introduce two methodological enhancements: (i) an H -size minibatch worst-case orthogonal matching pursuit algorithm that improves Sensor Selection (SSEL) while maintaining reconstruction accuracy, and (ii) memory optimisation techniques exploiting block matrix structures in vectorial problems. We demonstrate the effectiveness of the method through validation on a three-dimensional left ventricular model with simulated scar tissue. Starting with noise-free reconstruction, we systematically incorporate Gaussian noise and spatial sparsity mimicking realistic Magnetic Resonance Image acquisition protocols. Results show exceptional accuracy in noise-free conditions with relative $$L_2$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>L</mml:mi> <mml:mn>2</mml:mn> </mml:msub> </mml:math> error of $${1e-5}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mn>1</mml:mn> <mml:mi>e</mml:mi> <mml:mo>-</mml:mo> <mml:mn>5</mml:mn> </mml:mrow> </mml:math> , robust performance with 10% noise achieving relative $$L_2$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>L</mml:mi> <mml:mn>2</mml:mn> </mml:msub> </mml:math> error of $${1e-2}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mn>1</mml:mn> <mml:mi>e</mml:mi> <mml:mo>-</mml:mo> <mml:mn>2</mml:mn> </mml:mrow> </mml:math> , and effective reconstruction from sparse measurements with relative $$L_2$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>L</mml:mi> <mml:mn>2</mml:mn> </mml:msub> </mml:math> error of $${1e-2}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mn>1</mml:mn> <mml:mi>e</mml:mi> <mml:mo>-</mml:mo> <mml:mn>2</mml:mn> </mml:mrow> </mml:math> . The online reconstruction achieves sub-second computation times for a given patient geometry, enabling rapid clinical feedback and parameter studies that would be prohibitive with full Finite Element simulations, demonstrating significant potential for integration into clinical cardiac modelling workflows.

Computational Mechanics
University of Graz (AT), Medical University of Graz (AT), BioTechMed-Graz (AT)
L'Oreal USA, Istituto Nazionale di Alta Matematica "Francesco Severi", Partnership for Advanced Computing in Europe AISBL, Austrian Science Fund, Technische Universität Wien, Karl-Franzens-Universität Graz, BioTechMed-Graz, European Research Area Network on Cardiovascular Diseases, Gruppo Nazionale per il Calcolo Scientifico
Openalex Percentile: Top 100%
Cardiac Imaging and Diagnostics
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