Clinical characteristics, treatment status and prognosis analysis of elderly patients with ovarian cancer: a real world clinical study

Our real-world study demonstrates that just a small number of elderly patients with ovarian cancer received standard treatment and gene testing during treatment;those patients who accepted surgery, standardized treatment and maintenance had a better PFS and OS; the prognosis is even worse for patients who are older than 71;surgery and maintenance treatment are identified as independent prognostic factors for PFS, whereas surgery alone emerged as an independent prognostic factor for OS.While these findings provide valuable insights, it is important to note that this was a single-center retrospective analysis, and further validation in larger, prospective cohorts is warranted.

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Publication Details

Journal
Discover Oncology
Published
2025-12-06
DOI
https://doi.org/10.1007/s12672-025-04201-8
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical characteristics, treatment status and prognosis analysis of elderly patients with ovarian cancer: a real world clinical study

Ruxing Xi, Guoqing Wang, Xiaowei Wang, Jianbing Chen et al.
Discover Oncology
Ovarian cancer diagnosis and treatment
article

Clinical characteristics, treatment status and prognosis analysis of elderly patients with ovarian cancer: a real world clinical study

Ruxing Xi, Guoqing Wang, Xiaowei Wang, Jianbing Chen, Yahui Shen, Xi Liang
article en

Abstract

Our real-world study demonstrates that just a small number of elderly patients with ovarian cancer received standard treatment and gene testing during treatment;those patients who accepted surgery, standardized treatment and maintenance had a better PFS and OS; the prognosis is even worse for patients who are older than 71;surgery and maintenance treatment are identified as independent prognostic factors for PFS, whereas surgery alone emerged as an independent prognostic factor for OS.While these findings provide valuable insights, it is important to note that this was a single-center retrospective analysis, and further validation in larger, prospective cohorts is warranted.

Discover OncologyVol. 17(1)
Shanxi Medical University (CN), Xi'an Medical University (CN), Shanxi Provincial People’s Hospital (CN), First Hospital of Xi'an (CN)
Openalex Percentile: Top 50%
Ovarian cancer diagnosis and treatment
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