Recent advances in diverse reactions of γ-bromocrotonates and their derived allyl sulfonium salts

γ-Bromocrotonates and their derived allyl sulfonium salts serve as versatile synthons because they incorporate both an electron-withdrawing leaving group (bromine atom or sulfonium salt group) and a Michael acceptor (α,β-unsaturated ester group). This combination allows for the generation of various intermediates, leading to a wide range of subsequent transformations. Consequently, these synthons have garnered considerable attention, prompting the development of diverse methodologies and strategies for efficiently constructing functionalized organic molecules. In this review, we systematically summarize and elaborate on recent advances in diverse reactions of such versatile synthons. The discussed reactions are categorized according to γ-bromocrotonates and their derived allyl sulfonium salts acting as C1 synthons, C2 synthons, and C3 synthons, respectively, and provide detailed mechanistic insights. Additionally, this review highlights current challenges and future prospects for research in this field.

Authors

Institutions

Publication Details

Journal
Chemical Communications
Published
2025-12-04
DOI
https://doi.org/10.1039/d5cc04212g
Citations
1
Primary Topic
Sulfur-Based Synthesis Techniques
Type
article
Field-Weighted Citation Impact
0.94
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Recent advances in diverse reactions of γ-bromocrotonates and their derived allyl sulfonium salts

Nengzhong Wang, Dan Xiong, Hui Qin Yao, Nianyu Huang et al.
1 citations
Chemical Communications
Sulfur-Based Synthesis Techniques
0.94
article

Recent advances in diverse reactions of γ-bromocrotonates and their derived allyl sulfonium salts

Nengzhong Wang, Dan Xiong, Hui Qin Yao, Nianyu Huang, Lishuang Wang, Yong Chen, Linxuan Li, Xing Qu
article en
1 citations

Abstract

γ-Bromocrotonates and their derived allyl sulfonium salts serve as versatile synthons because they incorporate both an electron-withdrawing leaving group (bromine atom or sulfonium salt group) and a Michael acceptor (α,β-unsaturated ester group). This combination allows for the generation of various intermediates, leading to a wide range of subsequent transformations. Consequently, these synthons have garnered considerable attention, prompting the development of diverse methodologies and strategies for efficiently constructing functionalized organic molecules. In this review, we systematically summarize and elaborate on recent advances in diverse reactions of such versatile synthons. The discussed reactions are categorized according to γ-bromocrotonates and their derived allyl sulfonium salts acting as C1 synthons, C2 synthons, and C3 synthons, respectively, and provide detailed mechanistic insights. Additionally, this review highlights current challenges and future prospects for research in this field.

Chemical CommunicationsVol. 62(4)
China Three Gorges University (CN)
Openalex Percentile: Top 19%
Sulfur-Based Synthesis Techniques
0.94
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Recent advances in diverse reactions of γ-bromocrotonates and their derived allyl sulfonium salts — Nengzhong Wang, Dan Xiong, et al. · Chemical Communications (2025) | TGRS Research Map | TGRS