A Case Report of Primary Pleural Melanoma

Primary malignant pleural melanoma is an extremely rare neoplasm, and to the best of our knowledge, there have been 40 cases of primary pulmonary melanoma reported, but only 8 cases ‎of primary pleural melanoma in the literature. We herein report a rare case in which cytological and immunocytochemical analyses of pleural fluid and an ultrasonography (US)-guided biopsy of a pleural lesion were useful for diagnosing primary pleural melanoma. This case highlights the ‎importance of careful physical examinations, cytomorphologic and immunocytochemical analyses of ‎pleural fluid, as well as the utility of US-guided biopsy of the pleural lesions in the diagnosis of ‎primary pleural melanoma.