Cisplatin during radiation for head and neck cancer: insights from NRG Oncology experience
This manuscript offers a unified framework to optimize the use of cisplatin in chemoradiation protocols, improve adherence, reduce toxicity, and preserve oncologic efficacy. Our recommendations are particularly timely in the context of evolving clinical practices and recent cisplatin shortages. Insights from the NRG Oncology collaborative group aim to inform future trial designs and clinical practice guidelines, ensuring consistent and equitable care for patients with head and neck cancer.
Authors
- Lachlan McDowell (ORCID: https://orcid.org/0000-0002-4268-3079)
- Paul M. Harari (ORCID: https://orcid.org/0000-0002-6207-5505)
- Paul W. Gidley (ORCID: https://orcid.org/0000-0003-3706-8781)
- Jennifer H. Choe (ORCID: https://orcid.org/0000-0002-9279-0235)
- Musaddiq J. Awan (ORCID: https://orcid.org/0000-0002-1063-7932)
- Jed Abraham Katzel (ORCID: https://orcid.org/0000-0002-3037-018X)
- Christina Henson (ORCID: https://orcid.org/0000-0002-5419-4125)
- Loren K. Mell
- Luana Guimarães de Sousa (ORCID: https://orcid.org/0000-0002-3516-7105)
- Trisha M. Wise‐Draper (ORCID: https://orcid.org/0000-0002-7279-4028)
- James E. Bates (ORCID: https://orcid.org/0000-0001-7060-7156)
- Jimmy J. Caudell (ORCID: https://orcid.org/0000-0001-6417-2483)
- Jeffrey D. Sharon (ORCID: https://orcid.org/0000-0003-4892-5064)
- Beth M. Beadle (ORCID: https://orcid.org/0000-0001-5497-2831)
- A. Dimitrios Colevas (ORCID: https://orcid.org/0000-0003-3849-4264)
- Christina L. Runge (ORCID: https://orcid.org/0000-0003-0330-5857)
- Soumon Rudra (ORCID: https://orcid.org/0000-0002-1411-4880)
- Payal Anand (ORCID: https://orcid.org/0000-0001-6298-9262)
- Marc‐Elie Nader (ORCID: https://orcid.org/0000-0001-9295-0174)
- Nancy Y. Lee
- Sue S. Yom (ORCID: https://orcid.org/0000-0002-0779-7476)
- George Q. Yang (ORCID: https://orcid.org/0000-0003-4745-2592)
- Kaiwen Wang (ORCID: https://orcid.org/0000-0003-2881-8181)
Institutions
- University of Southern California (US)
- Memorial Sloan Kettering Cancer Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- University of Wisconsin–Madison (US)
- Emory University (US)
- University of California, San Francisco (US)
- Medical College of Wisconsin (US)
- Oklahoma City University (US)
- Princess Alexandra Hospital (AU)
- University of Oklahoma Medical Center (US)
- Moffitt Cancer Center (US)
- University of California San Diego (US)
- Piedmont Cancer Institute (US)
- Colorado Permanente Medical Group (US)
- Stanford Medicine (US)
- Princess Alexandra Hospital (GB)
- University of Oklahoma Health Sciences Center (US)
- University of Cincinnati (US)
- University of Oklahoma (US)
- Vanderbilt University Medical Center (US)
- University of Cincinnati Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- JNCI Journal of the National Cancer Institute
- Published
- 2025-12-04
- DOI
- https://doi.org/10.1093/jnci/djaf343
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00