Osteogenic biodegradable plates for cranioplasty in 6 patients across different age groups: clinical failure of promising concept? Patient series

Complications of varying severity, including implant deformation, resorption without adequate bone substitution, and poor cosmetic results, occurred in all patients. Based on these outcomes, the authors do not recommend CyberBone implants for routine clinical use in cranial reconstructions. Further material refinement and comprehensive safety studies are warranted before considering broader implementation in pediatric and adult populations. https://thejns.org/doi/10.3171/CASE25570.