Low Expression Levels of <i>MAOA</i> and <i>TPH1</i> Genes May Represent Risk Factors in Boys With Autism Spectrum Disorder—A Case–Control Study

This study is the first to investigate and establish a correlation between the expression levels of the MAOA and TPH1 genes and ASD using human blood samples. Low MAOA and TPH1 gene expression levels, may contribute to serotonergic dysregulation potentially acting as risk factors involved in ASD.

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Publication Details

Journal
International Journal of Developmental Neuroscience
Published
2025-12-01
DOI
https://doi.org/10.1002/jdn.70073
Primary Topic
Autism Spectrum Disorder Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Low Expression Levels of MAOA and TPH1 Genes May Represent Risk Factors in Boys With Autism Spectrum Disorder—A Case–Control Study

Hilal Akalın, Berrin Bilgiç, Sibelnur Avcıl, Seda Örenay-Boyacıoğlu
International Journal of Developmental Neuroscience
Autism Spectrum Disorder Research
article

Low Expression Levels of MAOA and TPH1 Genes May Represent Risk Factors in Boys With Autism Spectrum Disorder—A Case–Control Study

Hilal Akalın, Berrin Bilgiç, Sibelnur Avcıl, Seda Örenay-Boyacıoğlu
article en

Abstract

This study is the first to investigate and establish a correlation between the expression levels of the MAOA and TPH1 genes and ASD using human blood samples. Low MAOA and TPH1 gene expression levels, may contribute to serotonergic dysregulation potentially acting as risk factors involved in ASD.

International Journal of Developmental NeuroscienceVol. 85(8)
Adnan Menderes University (TR), Erciyes University (TR)
Openalex Percentile: Top 61%
Autism Spectrum Disorder Research
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