Depletion of myeloid cells in AG129 mice reduces the infection-mediated oxidative stress and restrains dengue virus-induced thymic atrophy
Thus, our study confirms that thymic atrophy does not depend on viremia level but on the interaction between immune cells and the virus, highlighting the contribution of infiltrating myeloid cells and, thus, ROS in DV-2-associated thymic atrophy.
Authors
- Surender Rawat (ORCID: https://orcid.org/0000-0002-9335-4961)
- Arup Banerjee (ORCID: https://orcid.org/0000-0002-0600-1763)
- Bagus Adhi Kusuma (ORCID: https://orcid.org/0000-0001-6970-1380)
- Amit Awasthi (ORCID: https://orcid.org/0000-0002-2563-1971)
- Srikanth Sadhu
- Tushar Kanti Maiti (ORCID: https://orcid.org/0000-0003-4721-827X)
- Oindrila Saha
- Sakshi Nimesh
Institutions
- Translational Health Science and Technology Institute (IN)
- Regional Centre for Biotechnology (IN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1186/s12964-025-02572-7
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00