Deciphering the Role of N-Acetyltransferase 10 in Thalamic Hemorrhage Through Integrative Multi-Omics and Experimental Validation
This study provides the first comprehensive molecular insights into the therapeutic potential of NAT10 inhibition in TH. Moreover, it identified NAT10 inhibitors and febuxostat as promising candidates for TH management, paving the way for future therapeutic development targeting NAT10 in this condition.
Authors
- Ju Gao (ORCID: https://orcid.org/0009-0003-4765-4554)
- Yaqun Li (ORCID: https://orcid.org/0000-0002-3073-0165)
- Tianfeng Huang (ORCID: https://orcid.org/0000-0001-7107-3045)
- Yinggang Xiao (ORCID: https://orcid.org/0000-0001-7372-7209)
Institutions
- Northern Jiangsu People's Hospital (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2025-11-21
- DOI
- https://doi.org/10.31083/jin44643
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00