Proteomic Characterization of Necroptosis-Related Proteins Reveals the Role of Endometrial Dysfunction in Predicting Pregnancy Outcomes in Polycystic Ovary Syndrome
Proteomic profiling revealed enrichment of the necroptosis pathway in the endometrium of patients with PCOS. The constructed model indicated preliminary predictive potential for pregnancy outcomes, suggesting that necroptosis may contribute to impaired endometrial receptivity.
Authors
- Wenhu Xin (ORCID: https://orcid.org/0000-0003-4349-5421)
- Fang Wang (ORCID: https://orcid.org/0000-0001-7895-374X)
- Chengbin Tao (ORCID: https://orcid.org/0009-0007-6349-1029)
- Kexin Wang (ORCID: https://orcid.org/0000-0002-4885-4262)
- Xiuli Tian (ORCID: https://orcid.org/0009-0004-0670-0646)
Institutions
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-11-27
- DOI
- https://doi.org/10.31083/fbl47322
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lanzhou University
- Natural Science Foundation of Gansu Province