AI-Driven Structural Elucidation of the Bacteriophage KP32: Decoding Its Molecular Arsenal Against Klebsiella Pneumoniae
Phage therapy is a potentially promising tool for controlling antimicrobial resistance (AMR). However, one limitation arises from the limited knowledge of their nature and mechanisms of action, as only a few phages have been structurally characterized. The reconstruction of entire phages is currently a viable strategy for elucidating their mechanistic properties, knowledge that will enhance their potential applications as therapeutic alternatives.
Authors
- Giovanni Barra (ORCID: https://orcid.org/0009-0000-1343-0876)
- Valeria Napolitano (ORCID: https://orcid.org/0000-0002-6709-8263)
- Flavia Squeglia (ORCID: https://orcid.org/0000-0001-9142-3313)
- Zuzanna Drulis‐Kawa (ORCID: https://orcid.org/0000-0002-4733-4660)
- Rita Berisio (ORCID: https://orcid.org/0000-0001-5025-6483)
- Mario Privitera (ORCID: https://orcid.org/0009-0003-7657-3278)
Institutions
- University of Campania "Luigi Vanvitelli" (IT)
- University of Wrocław (PL)
- Institute of Biostructure and Bioimaging (IT)
- National Research Council (IT)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-11-26
- DOI
- https://doi.org/10.31083/fbl46489
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00