Irisolidone Ameliorates Cyclophosphamide-Induced POI via Inhibiting Inflammatory Response

The present study demonstrates that Irisolidone can effectively alleviate CTX-induced POI by inhibiting abnormal inflammation. These findings suggest that Irisolidone holds promise as a novel therapeutic candidate for POI, thereby providing a potential new treatment strategy for clinical management of this condition.

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Publication Details

Journal
Frontiers in Bioscience-Landmark
Published
2025-11-26
DOI
https://doi.org/10.31083/fbl45744
Primary Topic
Nausea and vomiting management
Type
article
Field-Weighted Citation Impact
0.00
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article

Irisolidone Ameliorates Cyclophosphamide-Induced POI via Inhibiting Inflammatory Response

Shouye Ma, Mingjin Li, Jiyu Chen, Yaping Pei et al.
Frontiers in Bioscience-Landmark
Nausea and vomiting management
article

Irisolidone Ameliorates Cyclophosphamide-Induced POI via Inhibiting Inflammatory Response

Shouye Ma, Mingjin Li, Jiyu Chen, Yaping Pei, Zhenhong Wei, Xiaohong Chen, Huifang Wu, Xue Han
article en

Abstract

The present study demonstrates that Irisolidone can effectively alleviate CTX-induced POI by inhibiting abnormal inflammation. These findings suggest that Irisolidone holds promise as a novel therapeutic candidate for POI, thereby providing a potential new treatment strategy for clinical management of this condition.

Frontiers in Bioscience-LandmarkVol. 30(11)
Guiyang College of Traditional Chinese Medicine (CN), Guiyang Medical University (CN), Affiliated Hospital of Guizhou Medical University (CN), Gansu Provincial Hospital (CN)
Openalex Percentile: Top 42%
Nausea and vomiting management
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