Comprehensive Analysis of the ADCY Family and Identification of ADCY5 as a Prognostic Marker for Gastric Cancer
Our pan-cancer analysis nominates the ADCY family as a source of potential cancer biomarkers. We specifically validated ADCY5 in gastric cancer, establishing it as a promising prognostic biomarker with clinical and functional relevance, with significant implications for optimizing immunotherapy strategies and prognostic assessment in this malignancy.
Authors
- Yuzhe Zhang (ORCID: https://orcid.org/0000-0001-9216-5811)
- Yanke Li (ORCID: https://orcid.org/0009-0005-2366-7718)
- Lirong Yan (ORCID: https://orcid.org/0000-0001-7980-1238)
- Zhang Ye (ORCID: https://orcid.org/0000-0003-3495-5596)
Institutions
- University of Electronic Science and Technology of China (CN)
- First Hospital of China Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-11-26
- DOI
- https://doi.org/10.31083/fbl45527
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00