Curcuma longa L. Leaf and Pseudostem Extract Suppresses Inflammation in Cytokine-Stimulated HaCaT Keratinocytes and 12-O-Tetradecanoylphorbol-13-Acetate-Induced Ear Edema in Mice
Collectively, CLE exhibited potential as a natural anti-inflammatory agent by attenuating oxidative stress, downregulating inflammatory mediators, enhancing skin barrier function <i>in vitro</i>, and reducing ear edema <i>in vivo</i>.
Authors
- Ginnae Ahn (ORCID: https://orcid.org/0000-0002-1666-6048)
- Kirinde Gedara Isuru Sandanuwan Kirindage (ORCID: https://orcid.org/0000-0001-9364-3037)
- Arachchige Maheshika Kumari Jayasinghe (ORCID: https://orcid.org/0000-0003-3943-2452)
- Lei Wang (ORCID: https://orcid.org/0000-0002-3392-3712)
- Ji Soo Kim (ORCID: https://orcid.org/0000-0001-5307-4597)
- Seok Lee (ORCID: https://orcid.org/0009-0001-5013-5742)
- Kyungsook Jung (ORCID: https://orcid.org/0000-0002-0723-805X)
- Jihye Lee
- Hewayalage Madushika Kumari Ranasinghe
- Hitihami Mudiyanselage Chalani Bhagya Deshapriya
Institutions
- Chonnam National University (KR)
- National Institute of Biological Resources (KR)
- Institute for Advanced Engineering (KR)
- Ocean University of China (CN)
- Korea Research Institute of Bioscience and Biotechnology (KR)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-11-20
- DOI
- https://doi.org/10.31083/fbl42888
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00