Efficacy of Credelio Quattro™ (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) and Credelio™ (lotilaner) chewable tablets in the prevention of Borrelia burgdorferi transmission from infected Ixodes scapularis in dogs
The laboratory studies described herein confirm that a single dose of lotilaner, at the minimum effective dosage of 20 mg/kg, administered as Credelio Quattro, in combination with moxidectin, praziquantel, and pyrantel or Credelio, is effective for the prevention of transmission of B. burgdorferi from infected I. scapularis for a full month in dogs.
Authors
- Lisa Young (ORCID: https://orcid.org/0000-0001-8804-4152)
- Molly D. Savadelis
- Riaan Maree
- Abdelmoneim Mansour
- Scott Wiseman (ORCID: https://orcid.org/0000-0002-0269-6684)
- William Anderson (ORCID: https://orcid.org/0009-0003-7074-5892)
Institutions
- University of Georgia (US)
- Plasma Quest (United Kingdom) (GB)
- Animal Health Institute (US)
- ET International (United States) (US)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1186/s13071-025-07136-9
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00