Natural killer cell therapies in cancer: innovations, challenges, and future directions

NK cell-based therapies represent a promising avenue in cancer immunotherapy but require carefully designed solutions to overcome their inherent limitations. Advances in biomarker-guided patient selection, integration with existing treatment modalities, and international collaboration will be critical for translating NK cell biology into effective and durable clinical outcomes.

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Publication Details

Journal
Expert Opinion on Biological Therapy
Published
2025-12-02
DOI
https://doi.org/10.1080/14712598.2025.2601053
Primary Topic
Immune Cell Function and Interaction
Type
article
Field-Weighted Citation Impact
0.00
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article

Natural killer cell therapies in cancer: innovations, challenges, and future directions

Yachana Mishra, Abdelrahim M. Alqudah, Yahia El‐Tanani, Alaa A. A. Aljabali et al.
Expert Opinion on Biological Therapy
Immune Cell Function and Interaction
article

Natural killer cell therapies in cancer: innovations, challenges, and future directions

Yachana Mishra, Abdelrahim M. Alqudah, Yahia El‐Tanani, Alaa A. A. Aljabali, Vijay Kumar Mishra, Taher Hatahet, Esam Y. Qnais, Mohamed El‐Tanani, Omar Gammoh
article en

Abstract

NK cell-based therapies represent a promising avenue in cancer immunotherapy but require carefully designed solutions to overcome their inherent limitations. Advances in biomarker-guided patient selection, integration with existing treatment modalities, and international collaboration will be critical for translating NK cell biology into effective and durable clinical outcomes.

Expert Opinion on Biological TherapyVol. 25(12)
University College of the North (CA), Lovely Professional University (IN), Hashemite University (JO), Bangor University (GB), Royal Cornwall Hospital Trust (GB), Yarmouk University (JO), Ras al-Khaimah Medical and Health Sciences University (AE)
Openalex Percentile: Top 56%
Immune Cell Function and Interaction
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