Network Pharmacology Approach to Explore the Skin‐Lightening Compounds and Potential Mechanisms of Chinese Herbal Medicines
This study highlights the potential of network pharmacology as an effective approach for screening anti-melanogenic compounds from traditional skin-whitening herbs. Quercetin and acacetin were identified as key bioactive compounds that inhibit melanogenesis by modulating keratinocyte signaling pathways.
Authors
- Ling Jiang (ORCID: https://orcid.org/0000-0001-5082-097X)
- Xin‐Xin Lei
- Chuhan Fu (ORCID: https://orcid.org/0000-0003-0116-4675)
- Jing Chen (ORCID: https://orcid.org/0000-0001-9359-6568)
- Yixuan Liang (ORCID: https://orcid.org/0000-0002-0450-0526)
- Xixia Dai (ORCID: https://orcid.org/0000-0001-8915-883X)
Institutions
- Central South University (CN)
- Third People's Hospital of Hangzhou (CN)
- The Third Affiliated Hospital of Zhejiang Chinese Medical University (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/jocd.70562
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China