Association of sarcopenic obesity with dementia risk in a cohort of older women
This is the first longitudinal study to examine the association between SO and dementia using either the SOGLI or load-capacity models. In this cohort of older women, SO was associated with a lower risk of dementia-related hospitalisation. These findings suggest that the relationship between obesity and dementia risk in late life may differ from current evidence regarding midlife, indicating potential age-specific effects. Further research is needed to clarify the underlying mechanisms and generalisability of these observations to broader populations..
Authors
- Lorenzo M. Donini (ORCID: https://orcid.org/0000-0003-4692-4754)
- Joshua R. Lewis (ORCID: https://orcid.org/0000-0003-1003-8443)
- Blossom C. M. Stephan (ORCID: https://orcid.org/0000-0002-1235-360X)
- Carla M. Prado (ORCID: https://orcid.org/0000-0003-1160-0442)
- Marc Sim (ORCID: https://orcid.org/0000-0001-5166-0605)
- David L. Scott (ORCID: https://orcid.org/0000-0002-2198-4913)
- Mario Siervo (ORCID: https://orcid.org/0000-0001-5515-0944)
- Kun Zhu (ORCID: https://orcid.org/0000-0002-8723-7574)
- Zhongyang Guan (ORCID: https://orcid.org/0000-0003-0737-3929)
- Richard Prince
Institutions
- Edith Cowan University (AU)
- University of Alberta (CA)
- Curtin University (AU)
- Sir Charles Gairdner Hospital (AU)
- Monash University (AU)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Clinical Nutrition
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1016/j.clnu.2025.11.026
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00