<scp>miR</scp> ‐27a‐3p Upregulation and Netrin‐1 Deficiency Drive Inflammatory Responses and Nerve Degeneration in Patients With Diabetes
miR-27a-3p levels are elevated in subjects with DN and correlate with markers of inflammation, Netrin-1, and corneal nerve loss. miR-27a-3p could be a biomarker for DN, and miR-27a-3p/Netrin-1 crosstalk may be a promising therapeutic target for DN.
Authors
- Somnath Naskar (ORCID: https://orcid.org/0000-0002-0233-1378)
- Subhasish Pramanik (ORCID: https://orcid.org/0000-0003-0641-192X)
- Sucharita Sen Banerjee (ORCID: https://orcid.org/0009-0002-3067-8237)
- Rayaz Ahmed Malik (ORCID: https://orcid.org/0000-0002-7188-8903)
- Chinmay Saha (ORCID: https://orcid.org/0000-0002-6983-9336)
- Chiranjit Bose (ORCID: https://orcid.org/0000-0002-9506-8774)
- Pranab Kumar Sahana (ORCID: https://orcid.org/0000-0001-7176-4866)
- Asif Mondal (ORCID: https://orcid.org/0000-0002-5618-0333)
- Satinath Mukhopadhyay (ORCID: https://orcid.org/0000-0001-8033-5748)
- Bidisha Mukherjee
- Piyali Jati
Institutions
- Institute of Post Graduate Medical Education and Research (IN)
- Weill Cornell Medical College in Qatar (QA)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1111/ene.70449
- Primary Topic
- Axon Guidance and Neuronal Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Indian Council of Medical Research
- European Association for the Study of Diabetes