Genetic Evidence Implicating Gut Microbiota and Circulating Cytokines in Sjögren's Syndrome

This study provides compelling evidence for causal effects of gut microbiome composition and circulating cytokines on SS risk. Further mediation analysis suggests that these biological factors may operate independently to influence SS development.

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Publication Details

Journal
Journal of Clinical Laboratory Analysis
Published
2025-12-05
DOI
https://doi.org/10.1002/jcla.70136
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
0.00
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article

Genetic Evidence Implicating Gut Microbiota and Circulating Cytokines in Sjögren's Syndrome

Yuchen Cai, Xueyao Cai, Xia Ding, Wenjun Shi et al.
Journal of Clinical Laboratory Analysis
Salivary Gland Disorders and Functions
article

Genetic Evidence Implicating Gut Microbiota and Circulating Cytokines in Sjögren's Syndrome

Yuchen Cai, Xueyao Cai, Xia Ding, Wenjun Shi, Tianyi Zhou, Yu Li
article en

Abstract

This study provides compelling evidence for causal effects of gut microbiome composition and circulating cytokines on SS risk. Further mediation analysis suggests that these biological factors may operate independently to influence SS development.

Journal of Clinical Laboratory AnalysisVol. 40(1)
Shanghai Jiao Tong University (CN), Shanghai Ninth People's Hospital (CN), Shanghai Institute of Hematology (CN)
Openalex Percentile: Top 52%
Salivary Gland Disorders and Functions
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