Pseudo-apical hypertrophic cardiomyopathy phenotype in Takotsubo cardiomyopathy

Takotsubo cardiomyopathy can exhibit transient apical wall thickening during recovery, leading to a phenotypic overlap with apical hypertrophic cardiomyopathy. This pseudo-hypertrophic appearance is due to reversible myocardial oedema rather than genuine sarcomeric hypertrophy. We present a case demonstrating this diagnostic challenge and emphasising the importance of serial cardiac magnetic resonance imaging with tissue characterisation.

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Publication Details

Journal
The International Journal of Cardiovascular Imaging
Published
2025-12-06
DOI
https://doi.org/10.1007/s10554-025-03577-6
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
Type
article
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article

Pseudo-apical hypertrophic cardiomyopathy phenotype in Takotsubo cardiomyopathy

Gaetano Nucifora, Anna Reid, Mohamed Elzoghby
The International Journal of Cardiovascular Imaging
Takotsubo Cardiomyopathy and Associated Phenomena
article

Pseudo-apical hypertrophic cardiomyopathy phenotype in Takotsubo cardiomyopathy

Gaetano Nucifora, Anna Reid, Mohamed Elzoghby
article en

Abstract

Takotsubo cardiomyopathy can exhibit transient apical wall thickening during recovery, leading to a phenotypic overlap with apical hypertrophic cardiomyopathy. This pseudo-hypertrophic appearance is due to reversible myocardial oedema rather than genuine sarcomeric hypertrophy. We present a case demonstrating this diagnostic challenge and emphasising the importance of serial cardiac magnetic resonance imaging with tissue characterisation.

The International Journal of Cardiovascular ImagingVol. 42(2)
Manchester Academic Health Science Centre (GB), University of Manchester (GB), Wythenshawe Hospital (GB)
Openalex Percentile: Top 44%
Takotsubo Cardiomyopathy and Associated Phenomena
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Pseudo-apical hypertrophic cardiomyopathy phenotype in Takotsubo cardiomyopathy — Gaetano Nucifora, Anna Reid, et al. · The International Journal of Cardiovascular Imaging (2025) | TGRS Research Map | TGRS