Progress and Perspectives in Allogeneic Cell‐Based Pulp Regeneration

Despite encouraging preliminary results, significant limitations remain in the establishment of standardised protocols and the development of reliable techniques for longitudinal cell tracking. In future research, optimised delivery systems, immune-evasive cell engineering and rigorous clinical trial designs should be optimised to advance REPs towards predictable, clinically viable therapies.

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Publication Details

Journal
International Endodontic Journal
Published
2025-12-05
DOI
https://doi.org/10.1111/iej.70080
Primary Topic
Mesenchymal stem cell research
Type
article
Field-Weighted Citation Impact
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article

Progress and Perspectives in Allogeneic Cell‐Based Pulp Regeneration

Leyi Chen, Jianguang Xu, Lee Yan Lam, Y. Y. Chen et al.
International Endodontic Journal
Mesenchymal stem cell research
article

Progress and Perspectives in Allogeneic Cell‐Based Pulp Regeneration

Leyi Chen, Jianguang Xu, Lee Yan Lam, Y. Y. Chen, Xin Li, Yuchen Zhang, Shulan Lin, Mingxin Hu
article en

Abstract

Despite encouraging preliminary results, significant limitations remain in the establishment of standardised protocols and the development of reliable techniques for longitudinal cell tracking. In future research, optimised delivery systems, immune-evasive cell engineering and rigorous clinical trial designs should be optimised to advance REPs towards predictable, clinically viable therapies.

International Endodontic JournalVol. 59(4)
Anhui Medical University (CN), Stomatology Hospital (CN), Southern Medical University Shenzhen Hospital (CN), University of Hong Kong (HK)
Openalex Percentile: Top 41%
Mesenchymal stem cell research
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