Reduced Serum Soluble L‐Selectin Levels but Not <scp>PCSK9</scp> May Be Associated With Generalized Anxiety Disorder: A Case–Control Study

This study provides a better understanding of the relationship between inflammatory cytokines and GAD pathogenesis. The results indicate that sL-selectin, rather than PCSK9, may be associated with the pathophysiology of GAD. Still, more advanced investigations with greater sample sizes and extensive studies are essential to verify the probable diagnostic utility of serum sL-selectin levels.

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Publication Details

Journal
Journal of Clinical Laboratory Analysis
Published
2025-12-05
DOI
https://doi.org/10.1002/jcla.70144
Primary Topic
Adipokines, Inflammation, and Metabolic Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Reduced Serum Soluble L‐Selectin Levels but Not PCSK9 May Be Associated With Generalized Anxiety Disorder: A Case–Control Study

Shimanta Paul, Rashna Sharmin, Sharifa Sultana, Md. Aminul Haque et al.
Journal of Clinical Laboratory Analysis
Adipokines, Inflammation, and Metabolic Diseases
article

Reduced Serum Soluble L‐Selectin Levels but Not PCSK9 May Be Associated With Generalized Anxiety Disorder: A Case–Control Study

Shimanta Paul, Rashna Sharmin, Sharifa Sultana, Md. Aminul Haque, Md. Rabiul Islam, Abir Hasan Pranto, Md. Alamgir Hossain, Farzana Akter Munny
article en

Abstract

This study provides a better understanding of the relationship between inflammatory cytokines and GAD pathogenesis. The results indicate that sL-selectin, rather than PCSK9, may be associated with the pathophysiology of GAD. Still, more advanced investigations with greater sample sizes and extensive studies are essential to verify the probable diagnostic utility of serum sL-selectin levels.

Journal of Clinical Laboratory AnalysisVol. 40(1)
Daffodil International University (BD), University of Dhaka (BD), Bangladesh Institute of Research and Rehabilitation for Diabetes Endocrine and Metabolic Disorders (BD), University of Asia Pacific (BD), BRAC University (BD)
Openalex Percentile: Top 50%
Adipokines, Inflammation, and Metabolic Diseases
DOIOpen Access PDFOpenAlex
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Reduced Serum Soluble L‐Selectin Levels but Not <scp>PCSK9</scp> May Be Associated With Generalized Anxiety Disorder: A Case–Control Study — Shimanta Paul, Rashna Sharmin, et al. · Journal of Clinical Laboratory Analysis (2025) | TGRS Research Map | TGRS