Epilepsy-Induced Neurodegeneration and Its Therapeutic Interventions

Epilepsy is a disease that is recognized not only as a disorder of recurrent seizures but also for its association with neurodegeneration. This bibliometric analysis aims to assess the scientific outputs, trends, and key contributors to epilepsy-induced degeneration and the treatments aimed at intervening in neuronal damage. The Web of Science yielded a total of 662 publications between 1989 and 2025. The analysis identifies many key terms associated with epilepsy and neurodegeneration, including seizures, hippocampus, epileptogenesis, and oxidative stress. With the rise in research on this topic in recent years, there is growing potential for developing therapies that may prevent or reverse neurodegeneration in patients with epilepsy.