Use of benzodiazepine receptor agonists in different pregnancy trimesters and risk of maternal and neonatal outcomes: a propensity weighted cohort study in Taiwan
This study observed a small but statistical association between BZRA exposure and several adverse pregnancy outcomes, which extended from the pre-pregnancy period through all trimesters. Clinicians should carefully weigh the risks and benefits when treating women who are pregnant or planning pregnancy.
Authors
- Liang-Hsuan Chen (ORCID: https://orcid.org/0000-0002-5749-6962)
- Yi-Lin Chiang
- Sheng-Yin To (ORCID: https://orcid.org/0009-0007-5996-2879)
- Ming‐Fa Hsieh (ORCID: https://orcid.org/0000-0001-5254-1341)
- Wen-Chi Huang (ORCID: https://orcid.org/0000-0001-5556-1460)
- Li‐Ting Kao (ORCID: https://orcid.org/0000-0003-0692-7408)
- Ke‐Ting Pan (ORCID: https://orcid.org/0000-0003-0338-1083)
- Ruei-Siang Yu
- Huiwen Yang (ORCID: https://orcid.org/0009-0003-5768-8424)
Institutions
- Tri-Service General Hospital (TW)
- Chung Yuan Christian University (TW)
- Chang Gung Memorial Hospital (TW)
- Hualien Armed Forces General Hospital (TW)
- National Defense University (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1186/s12884-025-08549-1
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 0.00