Low-Cost CNC-Based media dispensing system for biotechnology laboratories

This report outlines the development and implementation of a Computer Numerical Control (CNC) based Automated Media Dispensing System (AMDS) in a plant biotechnology research laboratory. The AMDS, a dual-channel liquid dispensing system, underwent comprehensive testing and refinement over a two-year period. Designed to serve the production demand for a commercial transformation pipeline, the system represents an initial automation step to replace manual media dispensing operations. Performance evaluation demonstrates that this iteration surpasses manual dispensing metrics, achieving a process capability index (Cpk) of 2.28 compared to 1.43 for manual operations, while maintaining comparable time per tray efficiency. The system delivers significant ergonomic benefits by reducing prolonged standing periods associated with manual dispensing tasks. Building upon established automated dispensing principles, the custom-built AMDS achieves core functionality while reducing the barrier to entry, with an estimated material cost of approximately one-fiftieth that of more comprehensive market solutions. The system's modular architecture facilitates future modifications and adaptations, positioning it as a valuable tool for addressing evolving research needs in plant biotechnology while enabling broader adoption of automated dispensing technology.