The diagnostic value and mechanism of miR-127-3p in type 2 diabetes and complications of diabetic nephropathy
Upregulated miR-127-3p was involved in the progression of T2DM and DKD. In HG-induced HMC, down-regulated miR-127-3p improved cell viability and suppressed oxidative stress and inflammatory responses by negatively regulating ACO2.
Authors
- Guanfa Luo (ORCID: https://orcid.org/0009-0001-6336-4421)
- Lingbo Lv (ORCID: https://orcid.org/0009-0002-7809-8055)
- Lili Du (ORCID: https://orcid.org/0000-0002-9712-3925)
- Xin Zhang (ORCID: https://orcid.org/0000-0002-3499-2189)
- Xia Hong (ORCID: https://orcid.org/0000-0002-5937-8628)
- M. Cen
Institutions
- Huangshi Central Hospital (CN)
- Adam Mickiewicz University in Poznań (PL)
Publication Details
- Journal
- Hereditas
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1186/s41065-025-00618-x
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00