Expression of ACTR3 in cervical cancer and impact on immune cell infiltration and prognosis: A comprehensive analysis based on bulk RNA-Seq and single-cell RNA-Seq
This research elucidated a distinct signature linked to the PI3K/Akt/mTOR signaling pathway, particularly focusing on ACTR3, which plays a role in both the onset and advancement of CESC. Moreover, ACTR3 has the potential to act as a prognostic biomarker for patients diagnosed with CESC, thereby offering novel perspectives for the development of clinical therapeutic approaches.
Authors
- Xiu‐Juan Shang
- Wang Hong-dong (ORCID: https://orcid.org/0009-0003-7570-722X)
- Xu Chen (ORCID: https://orcid.org/0000-0002-9870-7287)
- Bohao Sun (ORCID: https://orcid.org/0000-0001-8401-1302)
- Yi‐Chen Wu (ORCID: https://orcid.org/0000-0002-9199-1203)
- Jianwei Li (ORCID: https://orcid.org/0000-0002-0262-3901)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-5346-7566)
- Hao Wang (ORCID: https://orcid.org/0000-0001-5268-8642)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Lianyungang Oriental Hospital (CN)
- Lianyungang Maternal and Children’s Hospital (CN)
- Children's Hospital of Zhejiang University (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1097/md.0000000000046316
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00