Autoimmune glial fibrillary acid protein astrocytopathy initially misdiagnosed as tuberculous meningitis: a case report

The clinical manifestations of autoimmune glial fibrillary acid protein astrocytopathy often include encephalitis, meningoencephalitis, meningoencephalomyelitis, and optic neuritis. These early manifestations are similar to those of central nervous system infections, where autoimmune glial fibrillary acid protein astrocytopathy is commonly misdiagnosed as tuberculous meningitis, early detection of glial fibrillary acid protein-immunoglobulin G antibody in cerebrospinal fluid is essential for differential diagnosis.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2025-12-05
DOI
https://doi.org/10.1186/s13256-025-05727-9
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Autoimmune glial fibrillary acid protein astrocytopathy initially misdiagnosed as tuberculous meningitis: a case report

Nan Mei, Lei Li, Qing Zhai, Hongwei� Jiang et al.
Journal of Medical Case Reports
Autoimmune Neurological Disorders and Treatments
article

Autoimmune glial fibrillary acid protein astrocytopathy initially misdiagnosed as tuberculous meningitis: a case report

Nan Mei, Lei Li, Qing Zhai, Hongwei� Jiang, Xinying Tian, Yan Cui
article en

Abstract

The clinical manifestations of autoimmune glial fibrillary acid protein astrocytopathy often include encephalitis, meningoencephalitis, meningoencephalomyelitis, and optic neuritis. These early manifestations are similar to those of central nervous system infections, where autoimmune glial fibrillary acid protein astrocytopathy is commonly misdiagnosed as tuberculous meningitis, early detection of glial fibrillary acid protein-immunoglobulin G antibody in cerebrospinal fluid is essential for differential diagnosis.

Journal of Medical Case ReportsVol. 20(1)
Hebei Medical University (CN), Hospital of Hebei Province (CN), Second Hospital of Hebei Medical University (CN)
Openalex Percentile: Top 47%
Autoimmune Neurological Disorders and Treatments
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