Creatine kinase and its muscle/brain isoenzyme as potential biomarkers for cardiovascular disease risk: A cross-sectional analysis of a population-based cohort
In this cross-sectional cohort, log CK and log CK-MB showed weak but statistically detectable associations with selected cardiovascular measures. These findings are hypothesis-generating and should be interpreted cautiously; they do not support clinical recommendations without prospective validation in larger studies.
Authors
- Melika Izadpanah (ORCID: https://orcid.org/0000-0003-1227-6875)
- Elham Dehghani
- Ashraf Alnattah
- M. Akbari (ORCID: https://orcid.org/0009-0000-9168-1507)
- Hamideh Safarian Bana
- Fatemeh Yarmohammadi (ORCID: https://orcid.org/0000-0002-0552-8766)
- Zhila Taherzadeh (ORCID: https://orcid.org/0000-0001-7185-970X)
- Elahe Pourahmadi
- Fatemeh Asgharian Rezae (ORCID: https://orcid.org/0000-0002-7214-6864)
- Saeid Eslami
Institutions
- Mashhad University of Medical Sciences (IR)
- Shahid Sadoughi University of Medical Sciences and Health Services (IR)
- Kermanshah University of Medical Sciences (IR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1371/journal.pone.0338025
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00