The influence of mesenchymal stem cells on the severity of hypoxic-ischemic brain damage in neonatal rats via serum cytokines
The serum levels of IL-6, IL-18, and TNF-α in rats are positively correlated with the severity of HIBD and can reflect the degree of brain tissue injury. They can be used for disease assessment; mesenchymal stem cell treatment can significantly reduce the serum levels of IL-6, IL-18, and TNF-α in HIBD rats, alleviate inflammatory responses, improve symptoms, and repair brain injury.
Authors
- Xinyi Liang (ORCID: https://orcid.org/0000-0002-3315-9742)
- Shuqiang Yue (ORCID: https://orcid.org/0000-0003-0026-6522)
- Feng‐Huei Lin (ORCID: https://orcid.org/0000-0002-2994-6671)
- Yuan Tan (ORCID: https://orcid.org/0009-0000-9332-9881)
- S. Lu (ORCID: https://orcid.org/0000-0002-1133-4060)
- Ze-Ping Huang (ORCID: https://orcid.org/0009-0006-1763-022X)
Institutions
- Guilin Medical University (CN)
Publication Details
- Journal
- IBRO Neuroscience Reports
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.ibneur.2025.12.002
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00