Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker of Disease Severity in Community-Acquired Pneumonia Among Hospitalized Patients From Northeast India

A strong positive correlation (r = 0.72) was noted between the NLR and CURB-65 score. A level of NLR ≥ 9.5 anticipated the need for intensive care unit (ICU) admission (40.74%, n=66 out of 162), while NLR ≥ 16 was associated with a higher death rate (80%, n=16; out of 20 deaths) compared to NLR <16 (20%, n=4). Most patients (55%) were middle-aged men. Right middle zone pneumonia (22.8%) was the most frequent radiological finding, while 85.18% patients had sterile sputum culture. Both Klebsiella pneumoniae (6.2%) and Streptococcus pneumoniae (6.2%) were the most typical organisms noted in the culture specimen. Conclusion: An elevated NLR is a strong predictor of disease severity, ICU requirement and mortality amongst Indian CAP patients.

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Journal
Cureus
Published
2025-12-05
DOI
https://doi.org/10.7759/cureus.98524
Primary Topic
Pneumonia and Respiratory Infections
Type
article
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article

Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker of Disease Severity in Community-Acquired Pneumonia Among Hospitalized Patients From Northeast India

Pallav Deka, A. Banerjee, Abhisek Ghosh, Akash Batta et al.
Cureus
Pneumonia and Respiratory Infections
article

Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker of Disease Severity in Community-Acquired Pneumonia Among Hospitalized Patients From Northeast India

Pallav Deka, A. Banerjee, Abhisek Ghosh, Akash Batta, Deepak Pandey, Dibya Jyoti Sharma
article en

Abstract

A strong positive correlation (r = 0.72) was noted between the NLR and CURB-65 score. A level of NLR ≥ 9.5 anticipated the need for intensive care unit (ICU) admission (40.74%, n=66 out of 162), while NLR ≥ 16 was associated with a higher death rate (80%, n=16; out of 20 deaths) compared to NLR <16 (20%, n=4). Most patients (55%) were middle-aged men. Right middle zone pneumonia (22.8%) was the most frequent radiological finding, while 85.18% patients had sterile sputum culture. Both Klebsiella pneumoniae (6.2%) and Streptococcus pneumoniae (6.2%) were the most typical organisms noted in the culture specimen. Conclusion: An elevated NLR is a strong predictor of disease severity, ICU requirement and mortality amongst Indian CAP patients.

CureusVol. 17(12)
Silchar Medical College and Hospital (IN), Dayanand Medical College & Hospital (IN)
Openalex Percentile: Top 50%
Pneumonia and Respiratory Infections
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Neutrophil-to-Lymphocyte Ratio as a Prognostic Marker of Disease Severity in Community-Acquired Pneumonia Among Hospitalized Patients From Northeast India — Pallav Deka, A. Banerjee, et al. · Cureus (2025) | TGRS Research Map | TGRS