Reactor and kinetic study advances for highly acidic solvolysis-mediated Friedel–Crafts reaction

This study presents a kinetic model that simulates the consumption of 4-hydroxybenzoic acid (4-HBA), the formation of di-isopropyl benzoic acid (DIPBA) via a Friedel–Crafts alkylation reaction, and the generation of key impurities.

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Publication Details

Journal
Reaction Chemistry & Engineering
Published
2025-12-05
DOI
https://doi.org/10.1039/d5re00379b
Primary Topic
Chemical Reaction Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Reactor and kinetic study advances for highly acidic solvolysis-mediated Friedel–Crafts reaction

Lane B. Carasik, C. H. Bailey, Thomas D. Roper, Matthew Glace et al.
Reaction Chemistry & Engineering
Chemical Reaction Mechanisms
article

Reactor and kinetic study advances for highly acidic solvolysis-mediated Friedel–Crafts reaction

Lane B. Carasik, C. H. Bailey, Thomas D. Roper, Matthew Glace, Someshwar Nagamalla, Connor Donlan, Gabrielle Broussard
article en

Abstract

This study presents a kinetic model that simulates the consumption of 4-hydroxybenzoic acid (4-HBA), the formation of di-isopropyl benzoic acid (DIPBA) via a Friedel–Crafts alkylation reaction, and the generation of key impurities.

Reaction Chemistry & EngineeringVol. 11(3)
Virginia Commonwealth University (US)
Openalex Percentile: Top 71%
Chemical Reaction Mechanisms
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