Avian Immunoglobulin Y Antibodies Targeting the Protruding or Shell Domain of Norovirus Capsid Protein Neutralize Norovirus Replication in the Human Intestinal Enteroid System
Our findings support the potential of IgY targeting norovirus P or S domains as a scalable, cost-effective strategy for preventing norovirus infection and disease.
Authors
- Mohamed Ichou (ORCID: https://orcid.org/0000-0001-6635-8505)
- Paul Alan Cox (ORCID: https://orcid.org/0000-0001-6401-2981)
- Lijuan Yuan (ORCID: https://orcid.org/0000-0003-0709-5228)
- Ming Xia (ORCID: https://orcid.org/0000-0002-0408-5828)
- S Vadlamudi
- Julius G. Goepp (ORCID: https://orcid.org/0000-0001-9449-968X)
- Ming Tan (ORCID: https://orcid.org/0000-0002-6489-5507)
- Peng Zhou (ORCID: https://orcid.org/0000-0002-1744-5167)
- Charlotte Nyblade
- Mathew Landivar
- Alice Leruth
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- University of Alabama (US)
- Virginia–Maryland College of Veterinary Medicine (US)
- Virginia Tech (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Vaccines
- Published
- 2025-12-05
- DOI
- https://doi.org/10.3390/vaccines13121228
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00